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“You really have to be like irrationally in love with the movie that you’re making,” Duplass said. “We’re really standing on the shoulders of the Cayton-Holland family in Denver who got hit with something surprising and unbelievable. It’s the story not only of how they survived it but came through better people.”

The film, “See You When I See You,” is having its world premiere Tuesday at the where it is seeking distribution. It stars , , David Duchovny, Hope Davis and Lucy Boynton.

“I kind of see it an heir to their film ‘The Big Sick,’” Duplass said, of Nanjiani and Gordon's Oscar-nominated romantic comedy.

Putting Raiff in the lead role over a more established movie star was an unconventional choice, to say the least, but Duplass was certain it was the right one. He’s been Raiff’s de facto mentor since before Raiff . He saw in him a range that he hadn't quite observed in some of his peers.

“He’s just so talented and smart and funny and emotionally available,” Duplass said. “Frankly there aren’t a lot of 27-year-olds who are all those things.” (Raiff is now 28).

Rounding out the cast with more well-known names was then non-negotiable. But Duplass has noticed in the past 10 to 15 years that it’s harder to get big name actors to join smaller art movies. Part of that, he said, is that actors are making “so much money in TV” and that the talent agencies are gatekeeping their talent on the off chance that a last minute offer will come in for one episode or a limited series.

He credits Dever, Duchovny, Davis and Boynton for being willing to commit to this film in spite of everything.

“It’s not a lot of money,” Duplass said. “These people are people who want to make art and who really were willing to take a chance and, you know, make something crazy with me.”

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